2.one Crucial Dosage and Administration Directions Administer promethazine HCl and codeine phosphate oral solution via the oral route only. Always use an exact milliliter measuring system when administering promethazine HCl and codeine phosphate oral solution to make certain the dose is measured and administered accurately.
Overdose of codeine in adults has become connected with lethal respiratory depression, and the use of codeine in little ones more youthful than twelve years of age has actually been associated with deadly respiratory melancholy when used as advisable [see Warnings and Safeguards (five.
Browse the Medication Manual provided by your pharmacist Before you begin using promethazine/phenylephrine/codeine and every time you can get a refill. If you have any issues, request your physician or pharmacist.
Health care vendors are strongly encouraged: to accomplish a REMS-compliant schooling application; counsel patients and/or their caregivers, with every prescription, on Protected use, critical challenges, storage, and disposal; emphasize to patients and their caregivers the significance of examining the Medication Manual every time it truly is supplied by their pharmacist; and take into consideration other instruments to boost individual, domestic, and Group safety.
If concomitant use is warranted, cautiously notice the patient, particularly throughout treatment initiation. Discontinue promethazine HCl and codeine phosphate oral Alternative if serotonin syndrome is suspected.
Don't raise your dose or use this products a lot more generally or for lengthier than prescribed. Your issue will likely not enhance any quicker, and also get more info your hazard of Negative effects will enhance.
Patients really should be instructed to not discontinue this drug without initial speaking about a tapering strategy with their Health care provider.
After codeine enters your process, your body breaks it down and converts it into morphine. Codeine is classed being a depressant, meaning it slows down your nervous method, which includes your breathing price.
The codeine in promethazine HCl and codeine phosphate oral solution may cause spasm of the sphincter of Oddi, causing a rise in biliary tract stress.
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By way of example, someone that snorts regular cocaine may be able to deal with three lines. After they try to do the same with pure cocaine, it may cause overdose that results in cardiac arrest and Loss of life.
These amenities typically perform carefully with family members, which is frequently a very important component of their remedy setting up for young people.
CONDITIONS OF USE: The data With this database is meant to health supplement, not substitute for, the skills and judgment of healthcare gurus. The knowledge just isn't intended to deal with all attainable utilizes, Instructions, precautions, drug interactions or adverse consequences, nor really should it be construed to point that utilization of a particular drug is safe, correct or powerful for you personally or anyone else.
In scenarios of overdose, You should use naloxone to briefly reverse the consequences of codeine as well as other opioids. It have to be specified immediately, not more than twenty to thirty minutes once the codeine continues to be taken.